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HIT218637857
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HIT218637857
  • HIT ID:HIT218637857
  • Cas No:63701-56-4
  • Common Name:(S)-Baclofen hydrochloride
  • alias:S(-)-Baclofen hydrochloride, S(-)-Baclofen HCl
    alias:S(-)-Baclofen hydrochloride, S(-)-Baclofen HCl
  • IUPAC:(3S)-4-amino-3-(4-chlorophenyl)butanoic acid hydrochloride
    IUPAC:(3S)-4-amino-3-(4-chlorophenyl)butanoic acid hydrochloride
  • InChIKey:WMNUVYYLMCMHLU-DDWIOCJRSA-N
  • Molecular Formula:C10H13Cl2NO2
  • Molecular Weight:250.12
  • Hydrogen Bond Donor (HBD):2
  • Hydrogen Bond Acceptor (HBA):3
  • LogP:-0.62
  • SMILES:Cl.NC[C@@H](CC(O)=O)c1ccc(Cl)cc1
    SMILES:Cl.NC[C@@H](CC(O)=O)c1ccc(Cl)cc1
  • (S)-baclofen (also known as L-baclofen), an enantiomer of baclofen, directly mimics the action of GABA-B receptors. In the treatment of trigeminal neuralgia, L-baclofen demonstrates significantly improved efficacy compared to racemic baclofen.
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