Name: BMS-195270
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HIT ID:HIT218701233
Cas No:202822-23-9
Common Name:BMS-195270
alias:UNII-20UM0T170J, SCHEMBL5754043, CHEMBL13637, BMS195270, BMS 195270
alias:UNII-20UM0T170J, SCHEMBL5754043, CHEMBL13637, BMS195270, BMS 195270
IUPAC:1-(5-chloro-2-hydroxyphenyl)-3-[2-(trifluoromethyl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
IUPAC:1-(5-chloro-2-hydroxyphenyl)-3-[2-(trifluoromethyl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
InChIKey:PHWHYZMFGGOJEU-UHFFFAOYSA-N

Molecular Formula:C15H9ClF3N3O2
Molecular Weight:355.7
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Oc1ccc(Cl)cc1-n1nc([nH]c1=O)-c1ccccc1C(F)(F)F
SMILES:Oc1ccc(Cl)cc1-n1nc([nH]c1=O)-c1ccccc1C(F)(F)F

BMS-195270 is a tissue-specific inhibitor of bladder muscle tone and spontaneous contraction in rats. It can inhibit Carbachol-induced tone and inhibit calcium flux in isolated rat bladder tissue strips in an isolated bladder model.

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