Autophagy Compound Library
TargetMol

Autophagy Compound Library

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by AnyMol contains 2000 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

  • All products & services are for research use only. Not for human or veterinary or therapeutic use.
L3200
Product Number: L3200
  • Pack Size
  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
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Technical Information

Product Description
  • Product Description:
    • A unique collection of 2000 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
    • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
    • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
    • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
    • Structurally diverse, medicinally active, and cell permeable;
    • NMR and HPLC validated to ensure high purity and quality;
  • Packaging And Storage:
    • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
    • Shipped with blue ice
    • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.
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Compound Library Composition
Autophagy
Apoptosis
PI3K
Akt
mTOR
Antibacterial
NF-κB
AMPK
Endogenous Metabolite
GSK-3
Others
p38 MAPK
ROS
Antibiotic
Parasite
ERK
Mitophagy
CDK
Caspase
CXCR
Reactive Oxygen Species
DNA/RNA Synthesis
HIV Protease
Ferroptosis
COX
Interleukin
JNK
VEGFR
S6 Kinase
ATM/ATR
Potassium Channel
STAT
DNA-PK
Antifungal
Bcl-2 Family
Cytochromes P450
TNF
ATG
Src
PPAR
PKC
Adrenergic Receptor
Nrf2
Wnt/beta-catenin
Calcium Channel
Virus Protease
MMP
PDK
EGFR
Retinoid Receptor
HDAC
5-HT Receptor
AChR
NO Synthase
Bcr-Abl
SARS-CoV
TLR
PARP
Topoisomerase
Mitochondrial Metabolism
Ras
PKA
LRRK2
FLT
HSV
CaMK
Influenza Virus
Dehydrogenase
Antioxidant
JAK
PDGFR
TGF-beta/Smad
PI4K
Microtubule Associated
HIF/HIF Prolyl-Hydroxylase
PERK
Beta Amyloid
IL Receptor
Aurora Kinase
MEK
HMG-CoA Reductase
Phosphatase
Raf
MAPK
c-Kit
Estrogen/progestogen Receptor
TRP/TRPV Channel
MDM-2/p53
ATPase
PDE
PTEN
HSP
Casein Kinase
FGFR
CFTR
Dopamine Receptor
FXR
FAAH
Sodium Channel
Nucleoside Antimetabolite/Analog
P-gp
ALK
IκB/IKK
c-Met/HGFR
Epigenetic Reader Domain
IGF-1R
FKBP
FAK
Histamine Receptor
Estrogen Receptor/ERR
ROCK
Sirtuin
GABA Receptor
p53
SIK
ROS Kinase
NOD-like Receptor (NLR)
Proteasome
Integrin
c-Myc
Glucocorticoid Receptor
Drug Metabolite
Prostaglandin Receptor
p62
Serotonin Transporter
Opioid Receptor
Chk
DUB
Trk receptor
Cannabinoid Receptor
Adenosine Receptor
Serine/threonin kinase
iGluR
Glucosidase
Antifection
Ligands for E3 Ligase
Cholinesterase (ChE)
Androgen Receptor
OXPHOS
HIF
c-RET
Anti-infection
Kras
FOXO
GPCR
Proton pump
NOS
Carbonic Anhydrase
Histone Methyltransferase
HCV Protease
DYRK
Cysteine Protease
Immunology/Inflammation related
Gamma-secretase
GluR
Lipoxygenase
transporter
Reverse Transcriptase
Phospholipase
Reductase
RAAS
Progesterone Receptor
MRP
HBV
Tyrosine Kinases
Glucokinase
glycosidase
MELK
PD-1/PD-L1
Monoamine Oxidase
ADC Cytotoxin
Transferase
DHFR
NADPH
Glutathione Peroxidase
Pim
Serine Protease
MAO
E1/E2/E3 Enzyme
RIP kinase
LDL
NMDAR
DPP-4
Fatty Acid Synthase
Hedgehog/Smoothened
Survivin
Antiviral
Pyroptosis
PLK
SGK
NOD
Tyrosinase
S1P Receptor
Ligands for Target Protein for PROTAC
Lipase
Tie-2
Cholecystokinin Receptor
Rho
Antifolate
ABC Transporter
CCR
DNA
c-Fms
ribosome
REV-ERB
DNA Methyltransferase
IRAK
Kinesin
PROTACs
RAR/RXR
Dynamin
Amino Acids and Derivatives
MyD88
LPL Receptor
Cell Cycle Arrest
Aryl Hydrocarbon Receptor
IDO
IAP
IRE1
GRK
P2X Receptor
BTK
Monoamine Transporter
Molecular Glues
Cadherin
Indoleamine 2,3-Dioxygenase (IDO)
Lipid
Beta-Secretase
STING
Ephrin Receptor
Histone Acetyltransferase
GST
CRISPR/Cas9
Syk
Sigma receptor
AhR
PGC-1α
Mdm2
Chloride channel
NPC1L1
ROR
YAP
Arginase
DNA Alkylator/Crosslinker
Arrestin
BACE
IFNAR
Necroptosis
NAMPT
RANKL/RANK
Amylase
Myosin
Adenylate cyclase
Annexin A
UGT
PAFR
DNA Alkylation
Angiotensin-converting Enzyme (ACE)
cAMP
PANoptosis
Norepinephrine
ATP Citrate Lyase
Acyltransferase
ASK
Acetyl-CoA Carboxylase
Protease
Complement System
Gap Junction Protein
DAPK
BMI-1
Lysosomal Autophagy
MLK
HER
Apelin receptor
Piezo Channel
NEDD8
Y Box Binding Protein 1
Na+/Ca2+ Exchanger
Cell wall
Histone Demethylase
gp120/CD4
GTPase
VDA
Melatonin Receptor
OCT
Photosensitizer
ASCT
B7
Hck
Liver X Receptor
LIM Kinase
PYK2
Glutaminase
NR4A
CSF-1R
LAG-3
Prolyl Endopeptidase (PREP)
FLAP
FABP
Glucagon Receptor
DNA gyrase
GlyT
Na-K-Cl cotransporter
Hexokinase
Guanylate cyclase
Smo
PROTAC Linker
MAGL
Bombesin Receptor
Vasopressin Receptor
ACK1
Endothelin Receptor
Somatostatin
Xanthine Oxidase
AXL
BCRP
PGE Synthase
MNK
AUTACs
Free radical scavengers
E3 Ligase Ligand-Linker Conjugates
Aminopeptidase
GPCR19
CPT
Decarboxylase
GluCls
NEDD4-1
GPX
FOXO3
KLF
Aquaporin
Hydroxylase
ATTECs
Discoidin Domain Receptor (DDR)
Neurokinin receptor
TAM Receptor
Tight Junction Protein
Thrombin
p97
Imidazoline Receptor
Vitamin

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