Target Identification

A drug target refers to the specific binding site where a drug directly interacts with biological macromolecules within the body. These targets mainly include receptors, enzymes, ion channels, transporters, and nucleic acids. The identification of drug targets not only helps establish the relationship between drug activity and cellular phenotypes or biological functions at specific sites, but also clarifies the mechanism of action of drugs. Furthermore, it enables the discovery of off-target effects and resistance mechanisms, the identification of new therapeutic targets, and the early prediction of potential side effects and toxicity during drug discovery. Ultimately, this helps reduce the risk of failure in drug development.