Sample Submission
Clients only need to provide compounds targeting the desired biological target (2–3 mg per compound). We will arrange the corresponding screening and testing services and deliver a professional analytical report.
Inquiry & Ordering
For any inquiries, please contact our team for prompt assistance.
The nuclear receptor superfamily comprises numerous transcription factors that play key regulatory roles in the development and homeostasis of multicellular organisms. Beyond their normal physiological functions, nuclear receptors are also involved in various pathological processes, making their role in biomedical research highly significant.
AnyMol provides high-quality, comprehensive nuclear receptor screening services. Both 96-well and 384-well plate formats are available to accelerate your drug discovery process.
| Target | Assay | Format |
|---|---|---|
| Androgen Receptor | TR-FRET/Cell based | 96/384 |
| Aryl Hydrocarbon Receptor | Cell based | 96/384 |
| Constitutive Androstane Receptor isoform 1/3 | TR-FRET/Cell based | 96/384 |
| ER alpha/beta | TR-FRET/Cell based | 96/384 |
| ERR (estrogen related receptor) alpha/beta/gamma | TR-FRET/Cell based | 96/384 |
| FXR (farnesoid X receptor) | TR-FRET | 96/384 |
| Glucocorticoid Receptor (GR) | Glucocorticoid Receptor (GR) | 96/384 |
| Liver Receptor Homolog-1 | Cell based | 96/384 |
| LXR (liver X receptor) alpha/beta | TR-FRET/Cell based | 96/384 |
| Mineralocorticoid Receptor (MR) | Cell based | 96/384 |
| Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) | Cell based | 96/384 |
| PPAR alpha/delta/gamma | TR-FRET/Cell based | 96/384 |
| Pregnane X Receptor | Cell based | 96/384 |
| Progesterone Receptor | TR-FRET/Cell based | 96/384 |
| RAR-related orphan receptor gamma (RORγ) | Cell based | 96/384 |
| Retinoic Acid Receptor (RAR) alpha/beta/gamma | TR-FRET/Cell based | 96/384 |
| Retinoid X Receptor (RXR) alpha/beta/gamma | TR-FRET/Cell based | 96/384 |
| TR(thyroid receptor) alpha/beta | TR-FRET/Cell based | 96/384 |
| TR-FRET LXR(liver X receptor)beta | TR-FRET | 96/384 |
| Vitamin D Receptor(VDR) | TR-FRET/Cell based | 96/384 |
Nuclear receptor screening models currently include both cell-based and protein-based approaches: Cell-based assays: Reporter gene assays; Cell-free assays: TR-FRET methods
