FDA-Approved Kinase Inhibitor Library 
Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases.
Targetmol's FDA-Approved Kinase Inhibitor Library contains 360 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors,PI 3-Kinase,CaM Kinase II,JAK,PKA,CDK,JNK,PKC,CKI II,MAPK,RAF,EGFR,MEK,SAPK,GSK,MLCK,Src-family,IKK,PDGFR,VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.
- All products & services are for research use only. Not for human or veterinary or therapeutic use.
- Pack Size
- 1 mg
- 10 μL x 10 mM (in DMSO)
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
Technical Information
Library Compound Information
Excel 
SDF - Product Description:
- A unique collection of 360 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
- All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
- Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
- NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.
- Packaging And Storage:
- Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
- Shipped with blue ice
- This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.
