Natural Product Derivatives Library 
Natural Product Derivatives Library
Historically, natural products have been pharma's treasure trove. According to the Natural Products Library Initiative at the Scripps Research Institute, "from 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (530/0) being either natural products or derived there from. "In a sense, this is not surprising. In nature, after all, creatures — and at the more basic level, structures, such as receptors and their ligands — have been co—evolving for billions of years.
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Product Number： NY1000
- Pack Size
- 10 μL x 10 mM (in DMSO)
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
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Technical Information
Library Compound Information
Excel 
SDF Product Description
- Product Description:
- The library consists of more than 4000 members belonging 22 scaffolds (average 180 compounds per scaffold).
- The library includes the following sub-libraries:
- Cytisine-based sub-library
- Matrine-based sub-library
- Podophyllotoxin-based sub-library
- Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc.
- TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members).
- NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc.).
- More than 90% purity for each library member confirmed by LC-MS or NMR analysis.
- Packaging And Storage:
- Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
- Shipped with blue ice
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