Nuclear Receptor Compound Library 
Nuclear receptors are a class of proteins, different from membrane receptors located in the cell membrane, found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors, thereby controlling the development, homeostasis, and metabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization and underlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease.
AnyMol collects 755 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery.
- All products & services are for research use only. Not for human or veterinary or therapeutic use.
- Pack Size
- 1 mg
- 10 μL x 10 mM (in DMSO)
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
Technical Information
Library Compound Information
Excel 
SDF - Product Description:
- A unique collection of 755 nuclear receptor signaling targeted compounds for high throughput and high content screening;
- Bioactivity and safety confirmed by pre-clinical research and clinical trials;
- Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
- Structurally diverse, medicinally active, and cell permeable;
- NMR and HPLC validated to ensure high purity and quality;
- Packaging And Storage:
- Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
- Shipped with blue ice
- This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.
