Pre-plated Diversity Sets

Pre-plated Diversity Sets

Life Chemicals presents its exclusive Pre-plated Diversity Sets composed of a total of 50,000 novel screening compounds with optimal physicochemical properties selected by dissimilarity search from the Life Chemicals HTS Compound Collection of newly synthesized molecules. They have been designed to facilitate phenotypic (cell-based) and target-based high throughput screening (HTS) efforts by providing access to a collection of structurally diverse small molecules in a convenient manner.
The Pre-plated Diversity Sets are ideal tools for drug discovery projects that require a wide range of chemical structure dissimilarity and quality drug-like and lead-like compounds to screen against new or validated biological targets from different classes, or where little information is available on a targeted protein structure.
For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap. They are complementary and can be combined to create more extensive diverse screening libraries (e.g., 30,000, 40,000, and up to 50,000 compounds in total).

  • All products & services are for research use only. Not for human or veterinary or therapeutic use.
LF1000
Product Number: LF1000
  • Pack Size
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
  • 500 μL
  • 5 μmol
  • 20 μmol
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Technical Information

Product Description
  • Product Description:

    Key features:
    The mean Tanimoto value of the 50k Diversity Set PS8 is 0.898, with even lower values in the subsets (calculated with ECFP fingerprints)
    No compound overlap with the previous edition (PS8 does not overlap with P7)
    Lipinski Rule of Five and Veber criteria-compliant compounds were selected
    Reagents, reactive or unstable molecules were excluded
    PAINS filter families A, B, and C were applied
    Lilly MedChem Rules compliance is guaranteed

  • Packaging And Storage:
    • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
    • Shipped with blue ice
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