Maybridge多样性化合物库
预制 Maybridge HitCreator 系列包括14,000种筛选化合物，源自对超过500,000种市售筛选化合物的严格分析。高多样性:基于Tanimoto 系数0.65 ，应用Daylight 指纹和谷本相似度计算，产生了一个异常多样化的商业化合物库，为找到热门内容提供了理想机会。高命中概率:化合物类似药物，符合Lipinski 的5法则和额外的过滤器。可靠性:库中的化合物已经过筛选，去除任何不合适的化学结构，使用我们的假阳性排除标准避免“假命中”。预制Maybridge HitCreator 系列包括14,000种筛选化合物，源自对超过500,000种市售筛选化合物的严格分析。使用基于standard Daylight fingerprints 和Tanimoto 相似度的聚类算法选择这些化合物。
- 陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。
- 规格
- 1 mg
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
技术资料
陶术生物化合物库目录 (78 MB) 
库化合物信息
Excel 
SDF - Product Description:
High diversity: applied Daylight fingerprints and Tanimoto similarity calculations based on the Tanimoto coefficient of 0.65 to produce an exceptionally diverse commercial library providing the best opportunity to find hits. High hit probability: compounds are drug-like, conforming to Lipinski’s Rule of 5 and additional filters. Reliability: compounds within the library have been screened to remove any inappropriate chemical structures, avoiding “false hits” using our false positives exclusion criteria. The pre-plated Maybridge HitCreator collection consists of 14,000 screening compounds, derived from a rigorous analysis of more than 500,000 commercially available screening compounds. These compounds have been selected using a clustering algorithm, based on standard Daylight fingerprints and Tanimoto similarity.
- 包装和储存:
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
寻找合适的化合物库
