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HIT100185968
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HIT100185968
  • HIT ID:HIT100185968
  • Cas No:20716-98-7
  • Common Name:Norlichexanthone
  • IUPAC:1,3,6-trihydroxy-8-methyl-9H-xanthen-9-one
    IUPAC:1,3,6-trihydroxy-8-methyl-9H-xanthen-9-one
  • InChIKey:AQZHBCDRWFMXIN-UHFFFAOYSA-N
  • Molecular Formula:C14H10O5
  • Molecular Weight:258.229
  • Hydrogen Bond Donor (HBD):3
  • Hydrogen Bond Acceptor (HBA):4
  • LogP:3.212
  • SMILES:Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12
    SMILES:Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12
  • Norlichexanthone has the potential to treat and/or prevent lifestyle-related diseases such as type 2 diabetes, metabolic syndrome, atherosclerosis and cardiovascular disease. Norlichexanthone has antibacterial and antimalarial activity, it has strong activity against Bacillus subtilis with an IC50 range of 1- 5uM, and also has strong inhibitory effect on the growth of methicillin-resistant Staphylococcus aureus with an IC50 of 20.95±1.56 uM.
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