Name: Gyrophoric acid
Rating: 5 (10 reviews)

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HIT ID:HIT100259176
Cas No:548-89-0
常用名:Gyrophoric acid
别名:石耳酸
IUPAC:4-[4-(2,4-dihydroxy-6-methylbenzoyloxy)-2-hydroxy-6-methylbenzoyloxy]-2-hydroxy-6-methylbenzoic acid
IUPAC:4-[4-(2,4-dihydroxy-6-methylbenzoyloxy)-2-hydroxy-6-methylbenzoyloxy]-2-hydroxy-6-methylbenzoic acid
InChI key:ATQPZSQVWCPVGV-UHFFFAOYSA-N

分子式:C24H20O10
分子量:468.414
氢键供体数 (HBD):5
氢键受体数 (HBA):10
LogP:6.42
SMILES:Cc1cc(O)cc(O)c1C(=O)Oc1cc(C)c(C(=O)Oc2cc(C)c(C(O)=O)c(O)c2)c(O)c1
SMILES:Cc1cc(O)cc(O)c1C(=O)Oc1cc(C)c(C(=O)Oc2cc(C)c(C(O)=O)c(O)c2)c(O)c1

Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton alterative activities of 2.5 J/cm(2) UVB in a dose-dependent manner, suggest that vulpinic and gyrophoric acids can be promising cosmetic ingredients to photo-protect human skin cells. Gyrophoric acid also has anti-proliferative/cytotoxic effect.

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