Name: Benserazide
Rating: 5 (10 reviews)

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HIT ID:HIT100440018
Cas No:14919-77-8;322-35-0
常用名:Benserazide
别名:Serazide, Ro-44602, Ro44602, Ro 44602
IUPAC:2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
IUPAC:2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
InChI key:BNQDCRGUHNALGH-UHFFFAOYSA-N

分子式:C10H15N3O5
分子量:257.246
氢键供体数 (HBD):7
氢键受体数 (HBA):7
LogP:-1.9928483
SMILES:NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
SMILES:NC(CO)C(=O)NNCc1ccc(O)c(O)c1O

Benserazide is an inhibitor of dopa decarboxylase. It is often given with levodopa in the treatment of Parkinson's to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose.

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