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- HIT ID:HIT101174644
- Cas No:19542-67-7
- Common Name:BAY 11-7082
- alias:BAY 11-7821
- InChI key:DOEWDSDBFRHVAP-KRXBUXKQSA-N
- Molecular Formula:C10H9NO2S
- Molecular Weight:207.25
- Hydrogen Bond Donor (HBD):0
- Hydrogen Bond Acceptor (HBA):2
- LogP:1.02
- BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that suppresses TNFα-induced IκBα phosphorylation (IC50=10 μM) and also inhibits the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM).
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