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HIT101254523
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HIT101254523
  • HIT ID:HIT101254523
  • Cas No:88495-63-0
  • Common Name:Artesunate
  • alias:WR-256283
  • IUPAC:4-oxo-4-{[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-yl]oxy}butanoic acid
    IUPAC:4-oxo-4-{[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-yl]oxy}butanoic acid
  • InChIKey:FIHJKUPKCHIPAT-AHIGJZGOSA-N
  • Molecular Formula:C19H28O8
  • Molecular Weight:384.425
  • Hydrogen Bond Donor (HBD):1
  • Hydrogen Bond Acceptor (HBA):7
  • LogP:2.934
  • SMILES:C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(=O)CCC(O)=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4
    SMILES:C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(=O)CCC(O)=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4
  • Artesunate (WR-256283) is a semisynthetic derivative of artemisinin and an inhibitor of STAT-3/EXP1. Water-soluble yet relatively unstable in neutral or acidic aqueous solutions, Artesunate is primarily employed for the treatment of malaria.
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