Name: Corynecin III
Rating: 5 (10 reviews)

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HIT ID:HIT102235182
Cas No:18048-95-8
常用名:Corynecin III
IUPAC:N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]-2-methylpropanamide
IUPAC:N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]-2-methylpropanamide
InChI key:IUBVSPMUTLUQHL-VXGBXAGGSA-N

分子式:C13H18N2O5
分子量:282.296
氢键供体数 (HBD):3
氢键受体数 (HBA):5
LogP:0.795
SMILES:CC(C)C(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O
SMILES:CC(C)C(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O

Corynecin III is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. aeruginosa, P. vulgaris, S. sonnei, S. typhosa, and K. pneumoniae (MICs = 2.6-83 μg/ml).

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