Name: (E/Z)-VU0029767
Rating: 5 (10 reviews)

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HIT ID:HIT102527953
Cas No:326001-01-8
常用名:(E/Z)-VU0029767
别名:VU-0029767, VU 0029767
IUPAC:2-[(4-ethoxyphenyl)amino]-N'-[(2-hydroxynaphthalen-1-yl)methylidene]acetohydrazide
IUPAC:2-[(4-ethoxyphenyl)amino]-N'-[(2-hydroxynaphthalen-1-yl)methylidene]acetohydrazide
InChI key:JWRJGCUSLSJMMD-UHFFFAOYSA-N

分子式:C21H21N3O3
分子量:363.417
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCOc1ccc(NCC(=O)NN=Cc2c(O)ccc3ccccc23)cc1 |w:12.11|
SMILES:CCOc1ccc(NCC(=O)NN=Cc2c(O)ccc3ccccc23)cc1 |w:12.11|

VU0029767 is a selective positive allosteric modulator of M1, a member of the muscarinic acetylcholine family of GPCRs (mAChRs). VU0029767 increases potency and efficacy of acetylcholine (ACh) at M1.

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