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- HIT ID:HIT102875895
- Cas No:2954-50-9
- 常用名:2-Aminotetralin
- 别名:2-AT
- InChI key:LCGFVWKNXLRFIF-UHFFFAOYSA-N
- 分子式:C10H13N
- 分子量:147.221
- 氢键供体数 (HBD):1
- 氢键受体数 (HBA):1
- LogP:1.9318997
- 2-Aminotetralin acts as a neuromodulatory agent by inhibiting serotonin (5-HT) and norepinephrine reuptake in the rat brain at a dose of 39.4 mg/kg. It triggers hypothermia in rats through intracisternal or intraperitoneal injection, while the implantation of crystals in the hypothalamus' medial preoptic area leads to hyperthermia. Additionally, it mimics (+)-amphetamine in a two-lever drug discrimination test among rats in a dose-dependent manner.
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