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HIT103028871
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HIT103028871
  • HIT ID:HIT103028871
  • Cas No:895470-67-4
  • Common Name:CP-312
  • alias:CP312, Cardioprotectant 312
  • IUPAC:2-[(4-chlorophenyl)sulfanyl]-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]acetamide
    IUPAC:2-[(4-chlorophenyl)sulfanyl]-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]acetamide
  • InChIKey:KAWIOCMUARENDQ-UHFFFAOYSA-N
  • Molecular Formula:C16H12ClN3OS2
  • Molecular Weight:361.86
  • Hydrogen Bond Donor (HBD):1
  • Hydrogen Bond Acceptor (HBA):5
  • LogP:4.16
  • SMILES:Clc1ccc(SCC(=O)Nc2nc(cs2)-c2ccccn2)cc1
    SMILES:Clc1ccc(SCC(=O)Nc2nc(cs2)-c2ccccn2)cc1
  • CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.
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