• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT103064654
有库存
HIT103064654
 sdf 文件
结构编辑
类似物检索
HIT103064654
  • HIT ID:HIT103064654
  • Cas No:875863-22-2
  • 常用名:STING Agonist C11
  • 别名:STING Agonist C11
  • IUPAC:3-methyl-1-(2-{[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-phenylacetyl)urea
    IUPAC:3-methyl-1-(2-{[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-phenylacetyl)urea
  • InChI key:KQKWXSQTTDLZSO-UHFFFAOYSA-N
  • 分子式:C19H18N4O3S
  • 分子量:382.44
  • 氢键供体数 (HBD):2
  • 氢键受体数 (HBA):4
  • LogP:2.997
  • SMILES:CNC(=O)NC(=O)C(Sc1nnc(o1)-c1ccc(C)cc1)c1ccccc1
    SMILES:CNC(=O)NC(=O)C(Sc1nnc(o1)-c1ccc(C)cc1)c1ccccc1
  • STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses grown in THF cells (EC90s = 16.44, 16.7, 18.84, 25.19, and 22.57 μM, respectively), an effect that is dependent on the presence of STING and the IFN-α/β receptor (IFNAR).
市场产品/服务共显示3个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 2,630.00
    1
  • 供应商
    EnamineSC
    规格
    货期
    4-6周
    纯度
    -
    ¥ 1,084.00
    1
  • 供应商
    UkrOrgSynthesisSC
    规格
    货期
    4-6周
    纯度
    -
    ¥ 1,096.00
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymol随时为您提供帮助。
电话：400-820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层