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HIT103197031
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HIT103197031
  • HIT ID:HIT103197031
  • Cas No:141992-47-4
  • Common Name:NSC 625987
  • alias:NSC-625987, NSC625987
  • IUPAC:1,4-dimethoxy-9,10-dihydroacridine-9-thione
    IUPAC:1,4-dimethoxy-9,10-dihydroacridine-9-thione
  • InChIKey:KFAKESMKRPNZTM-UHFFFAOYSA-N
  • Molecular Formula:C15H13NO2S
  • Molecular Weight:271.33
  • Hydrogen Bond Donor (HBD):1
  • Hydrogen Bond Acceptor (HBA):3
  • LogP:3.473806
  • SMILES:COc1ccc(OC)c2c1[nH]c1ccccc1c2=S
    SMILES:COc1ccc(OC)c2c1[nH]c1ccccc1c2=S
  • NSC 625987 is a selective, high-affinity CDK4 inhibitor with an IC50 of 0.2 μM for CDK4:cyclin D1. Its selectivity for CDK4 is >500-fold greater than for CDK2, making it suitable for studying p16-associated tumors.
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  • Supplier
    TargetMolSC
    Pack Size
    Estimated Lead Time
    1-3 days
    Purity
    99.01%
    $ 61.00
    1
  • Supplier
    Princeton BioMolecal ResearchBB
    Pack Size
    Estimated Lead Time
    4-6 weeks
    Purity
    -
    $ 1,430.00
    1

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