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HIT103240441
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HIT103240441
  • HIT ID:HIT103240441
  • Cas No:
  • Common Name:NRX-1532
  • alias:NRX1532, NRX 1532
  • IUPAC:2-oxo-N-[3-(1H-pyrazol-5-yl)phenyl]-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide
    IUPAC:2-oxo-N-[3-(1H-pyrazol-5-yl)phenyl]-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide
  • InChIKey:KRFAUNDDLPKBNF-UHFFFAOYSA-N
  • Molecular Formula:C16H11F3N4O2
  • Molecular Weight:348.285
  • Hydrogen Bond Donor (HBD):3
  • Hydrogen Bond Acceptor (HBA):3
  • LogP:1.7
  • SMILES:FC(F)(F)c1ccc(C(=O)Nc2cccc(c2)-c2ccn[nH]2)c(=O)[nH]1
    SMILES:FC(F)(F)c1ccc(C(=O)Nc2cccc(c2)-c2ccn[nH]2)c(=O)[nH]1
  • NRX-1532 is a small molecule that acts as an enhancer of the β-catenin:β-TrCP interaction.
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