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- HIT ID:HIT103302779
- Cas No:59-53-0
- 常用名:N-Acetyl-DL-penicillamine
- InChI key:MNNBCKASUFBXCO-UHFFFAOYSA-N
- 分子式:C7H13NO3S
- 分子量:191.25
- 氢键供体数 (HBD):3
- 氢键受体数 (HBA):3
- LogP:0.084
- N-Acetyl-DL-penicillamine is a chelating agent.1,2,3It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.1,2N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mice when administered following injection of methyl mercuric chloride. It decreases mercuric chloride-induced mortality in mice when administered orally at a dose of 1.6 mmol/kg.3N-Acetyl-DL-penicillamine is also an analog of SNAP that does not generate nitric oxide and has been used as a negative control in experiments using SNAP.4,5
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- 供应商TargetMol规格货期35日内发货纯度-¥ 3,850.001
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- 供应商UkrOrgSynthesis规格货期4-6周纯度-¥ 1,096.001
- 供应商AA Blocks规格货期4-6周纯度-待询1
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