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HIT103586942
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HIT103586942
  • HIT ID:HIT103586942
  • Cas No:693231-07-1
  • Common Name:BRD-K56819078
  • IUPAC:N-[2-({[(2-fluorophenyl)carbamoyl]methyl}sulfanyl)-1,3-benzothiazol-6-yl]-3,4-dimethoxybenzamide
    IUPAC:N-[2-({[(2-fluorophenyl)carbamoyl]methyl}sulfanyl)-1,3-benzothiazol-6-yl]-3,4-dimethoxybenzamide
  • InChIKey:LRMLVVSJYYACIX-UHFFFAOYSA-N
  • Molecular Formula:C24H20FN3O4S2
  • Molecular Weight:497.56
  • Hydrogen Bond Donor (HBD):2
  • Hydrogen Bond Acceptor (HBA):4
  • LogP:4.45
  • SMILES:COc1ccc(cc1OC)C(=O)Nc1ccc2nc(SCC(=O)Nc3ccccc3F)sc2c1
    SMILES:COc1ccc(cc1OC)C(=O)Nc1ccc2nc(SCC(=O)Nc3ccccc3F)sc2c1
  • BRD-K56819078, a Bcl-2 inhibitor, significantly reduces the burden of senescent cells and the mRNA expression of aging-related genes in the kidneys. It exerts its anti-aging effects by inhibiting cell apoptosis (apoptosis).
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