• CAS
  • HIT ID
  • Catalog
  • SMILES
  • Library
  • InChIKey

  • 中文
  • English
0
  2. Structural Search
  3. HIT103671874
In Stock
HIT103671874
 SDF File
Edit Structure
Find Similar
HIT103671874
  • HIT ID:HIT103671874
  • Cas No:353793-07-4
  • Common Name:Z640
  • IUPAC:2-(6,7-dimethyl-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-[4-(morpholin-4-yl)phenyl]acetamide
    IUPAC:2-(6,7-dimethyl-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-[4-(morpholin-4-yl)phenyl]acetamide
  • InChIKey:NUPBIIGSDCCPHO-UHFFFAOYSA-N
  • Molecular Formula:C22H26N4O3
  • Molecular Weight:394.475
  • Hydrogen Bond Donor (HBD):3
  • Hydrogen Bond Acceptor (HBA):7
  • LogP:1.93
  • SMILES:Cc1cc2NC(CC(=O)Nc3ccc(cc3)N3CCOCC3)C(=O)Nc2cc1C
    SMILES:Cc1cc2NC(CC(=O)Nc3ccc(cc3)N3CCOCC3)C(=O)Nc2cc1C
  • Z640 an aPKC agonist. Z640 was further confirmed as a non‑selective aPKC agonist that can activate the kinase activity of both PKCι and PKCζ. In the cell‑based assay, Z640 was found to protect neuronal cell lines from amyloid‑β (Aβ) oligomer‑induced cell death by reducing reactive oxygen species production and restore mitochondrial function. In addition, Z640 could reduce Aβ40 generation in a dose‑dependent manner and shift amyloid precursor protein processing towards the non‑amyloid pathway
Marketplace OffersShowing from 7 suppliers
  • Supplier
    TargetMolSC
    Pack Size
    Estimated Lead Time
    6-8 weeks
    Purity
    -
    $ 1,520.00
    1
  • Supplier
    ChemDivSC
    Pack Size
    Estimated Lead Time
    3-5 weeks
    Purity
    -
    $ 148.00
    1
  • Supplier
    LifechemicalsSC
    Pack Size
    Estimated Lead Time
    3-4 weeks
    Purity
    -
    $ 138.00
    1
  • Supplier
    ChembridgeSC
    Pack Size
    Estimated Lead Time
    3-4 weeks
    Purity
    -
    $ 88.00
    1
  • Supplier
    SpecsSC
    Pack Size
    Estimated Lead Time
    2-3 weeks
    Purity
    -
    $ 37.00
    1
  • Supplier
    OtavaSC
    Pack Size
    Estimated Lead Time
    4-6 weeks
    Purity
    -
    $ 62.00
    1
  • Supplier
    InnovapharmSC
    Pack Size
    Estimated Lead Time
    4-6 weeks
    Purity
    -
    Inquiry
    1

You cannot determine which compound library is the best fit for your project? Do you need a custom solution? AnyMol is always ready to help you.
：400-820-0310
TargetMol | Target Loading
Loading ~
Common Tools
SearchSign inBack to Top