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HIT103708159
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HIT103708159
  • HIT ID:HIT103708159
  • Cas No:74873-41-9
  • Common Name:Hepatoprotective agent-2
  • IUPAC:2-amino-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
    IUPAC:2-amino-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
  • InChIKey:MAOPIIGFJUIBSL-UHFFFAOYSA-N
  • Molecular Formula:C16H15N3
  • Molecular Weight:249.317
  • Hydrogen Bond Donor (HBD):2
  • Hydrogen Bond Acceptor (HBA):2
  • LogP:3.35
  • SMILES:Nc1nc2CCCCc2c(-c2ccccc2)c1C#N
    SMILES:Nc1nc2CCCCc2c(-c2ccccc2)c1C#N
  • Hepatoprotective agent-2 (compound 2a), a 4-phenyl-tetrahydroquinoline derivative, not only demonstrates significant hepatoprotective effects but also possesses antiapoptotic activity. It effectively mitigates chemically induced increases in hepatic indicators, which are symptomatic of liver damage [1].
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