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HIT103880444
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HIT103880444
  • HIT ID:HIT103880444
  • Cas No:1197911-63-9
  • Common Name:MMV1088447
  • alias:MMV-1088447, MMV 1088447
  • IUPAC:2-carbamoylphenyl 1-[(furan-2-yl)methyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate
    IUPAC:2-carbamoylphenyl 1-[(furan-2-yl)methyl]-2,5-dimethyl-1H-pyrrole-3-carboxylate
  • InChIKey:ONABHHAASBYICU-UHFFFAOYSA-N
  • Molecular Formula:C19H18N2O4
  • Molecular Weight:338.363
  • Hydrogen Bond Donor (HBD):1
  • Hydrogen Bond Acceptor (HBA):2
  • LogP:3.12
  • SMILES:Cc1cc(C(=O)Oc2ccccc2C(N)=O)c(C)n1Cc1ccco1
    SMILES:Cc1cc(C(=O)Oc2ccccc2C(N)=O)c(C)n1Cc1ccco1
  • MMV1088447 is a novel inhibitor of parasite growth. This compound shares characteristics with cells treated with nuclear hormone receptor (NHR) agonists/antagonists. By reducing host lipid metabolism, MMV1088447 significantly impedes the growth of parasites.
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