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HIT103902344
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HIT103902344
  • HIT ID:HIT103902344
  • Cas No:484049-04-9
  • Common Name:DPH
  • IUPAC:5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione
    IUPAC:5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione
  • InChIKey:MPQWYPLPWGUMJE-UHFFFAOYSA-N
  • Molecular Formula:C18H13FN4O2
  • Molecular Weight:336.326
  • Hydrogen Bond Donor (HBD):2
  • Hydrogen Bond Acceptor (HBA):3
  • LogP:2.747805
  • SMILES:Fc1ccc(cc1)-c1nn(cc1C1NC(=O)NC1=O)-c1ccccc1
    SMILES:Fc1ccc(cc1)-c1nn(cc1C1NC(=O)NC1=O)-c1ccccc1
  • DPH is a potent, cell-permeable activator of c-Abl, demonstrating significant enzymatic and cellular efficacy in stimulating c-Abl activation.
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