Name: VU0606170
Rating: 5 (10 reviews)

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HIT ID:HIT103906922
Cas No:879054-55-4
常用名:VU0606170
IUPAC:N-(5-chloro-2-methoxyphenyl)-2-{4-[(4-methylpiperidin-1-yl)sulfonyl]piperazin-1-yl}acetamide
IUPAC:N-(5-chloro-2-methoxyphenyl)-2-{4-[(4-methylpiperidin-1-yl)sulfonyl]piperazin-1-yl}acetamide
InChI key:MESKWLXKTLBNGU-UHFFFAOYSA-N

分子式:C19H29ClN4O4S
分子量:444.98
氢键供体数 (HBD):2
氢键受体数 (HBA):5
LogP:3.3
SMILES:COc1ccc(Cl)cc1NC(=O)CN1CCN(CC1)S(=O)(=O)N1CCC(C)CC1
SMILES:COc1ccc(Cl)cc1NC(=O)CN1CCN(CC1)S(=O)(=O)N1CCC(C)CC1

VU0606170 is a slack channels inhibitor and was shown to successfully decrease the malfunctioning spontaneous firing rate of cortical neurons, providing a potential avenue for achieving an anti-epileptic effect not previously attainable.

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