Name: Skyrin
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HIT ID:HIT103918227
Cas No:35144-94-6;602-06-2
Common Name:Skyrin
alias:Rhodophyscin, Endothianin
IUPAC:2,2',4,4',5,5'-hexahydroxy-7,7'-dimethyl-9H,9'H,10H,10'H-[1,1'-bianthracene]-9,9',10,10'-tetrone
IUPAC:2,2',4,4',5,5'-hexahydroxy-7,7'-dimethyl-9H,9'H,10H,10'H-[1,1'-bianthracene]-9,9',10,10'-tetrone
InChIKey:MQSXZQXHIJMNAF-UHFFFAOYSA-N

Molecular Formula:C30H18O10
Molecular Weight:538.464
Hydrogen Bond Donor (HBD):6
Hydrogen Bond Acceptor (HBA):10
LogP:7.317
SMILES:Cc1cc(O)c2C(=O)c3c(O)cc(O)c(c3C(=O)c2c1)-c1c(O)cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c12
SMILES:Cc1cc(O)c2C(=O)c3c(O)cc(O)c(c3C(=O)c2c1)-c1c(O)cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c12

Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines.

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