别名:U7524, U 7524, AOAA, Aminooxyacetic acid, 2-Aminooxyacetic acid
别名:U7524, U 7524, AOAA, Aminooxyacetic acid, 2-Aminooxyacetic acid
IUPAC:2-(aminooxy)acetic acid
IUPAC:2-(aminooxy)acetic acid
InChI key:NQRKYASMKDDGHT-UHFFFAOYSA-N
分子式:C2H5NO3
分子量:91.066
氢键供体数 (HBD):3
氢键受体数 (HBA):3
LogP:-0.591
SMILES:NOCC(O)=O
SMILES:NOCC(O)=O
U-7524, also known as AOAA and Aminooxyacetic acid, is an inhibitor of 4-aminobutyrate aminotransferase (GABA-T). AOAA is also a general inhibitor of pyridoxal phosphate (PLP)-dependent enzymes (this includes GABA-T). It functions as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes.