Name: Boc-NH-PEG5-azide
Rating: 5 (10 reviews)

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HIT ID:HIT105060349
Cas No:911209-07-9
常用名:Boc-NH-PEG5-azide
IUPAC:tert-butyl N-(17-azido-3,6,9,12,15-pentaoxaheptadecan-1-yl)carbamate
IUPAC:tert-butyl N-(17-azido-3,6,9,12,15-pentaoxaheptadecan-1-yl)carbamate
InChI key:PMTHVVYQUZJIEC-UHFFFAOYSA-N

分子式:C17H34N4O7
分子量:406.48
氢键供体数 (HBD):1
氢键受体数 (HBA):8
LogP:0.7620034
SMILES:CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCN=[N+]=[N-]
SMILES:CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Boc-NH-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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