Name: Azido-PEG5-amine
Rating: 5 (10 reviews)

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HIT ID:HIT105570098
Cas No:516493-93-9
常用名:Azido-PEG5-amine
IUPAC:17-azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
IUPAC:17-azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
InChI key:SVPBRIZYFJFLOL-UHFFFAOYSA-N

分子式:C12H26N4O5
分子量:306.363
氢键供体数 (HBD):1
氢键受体数 (HBA):8
LogP:-0.730094
SMILES:NCCOCCOCCOCCOCCOCCN=[N+]=[N-]
SMILES:NCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Azido-PEG5-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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