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HIT105727852
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HIT105727852
  • HIT ID:HIT105727852
  • Cas No:922029-50-3
  • 常用名:Angiogenesis inhibitor BT2
  • IUPAC:ethyl N-{9-ethyl-10-oxo-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl}carbamate
    IUPAC:ethyl N-{9-ethyl-10-oxo-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl}carbamate
  • InChI key:RLHBXNGNLUURTN-UHFFFAOYSA-N
  • 分子式:C18H18N2O4
  • 分子量:326.352
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):4
  • LogP:3.6
  • SMILES:CCOC(=O)Nc1ccc2Oc3ccccc3N(CC)C(=O)c2c1
    SMILES:CCOC(=O)Nc1ccc2Oc3ccccc3N(CC)C(=O)c2c1
  • Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, angiogenesis, and inflammation, interacting with MEK1, suppressing retinal CD31, pERK, VCAM-1, and VEGF-A165 expression.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1
  • 供应商
    LifechemicalsSC
    规格
    货期
    3-4周
    纯度
    -
    ¥ 990.00
    1

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