Name: 4-Methylumbelliferyl Caprylate
Rating: 5 (10 reviews)

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HIT ID:HIT106154492
Cas No:20671-66-3
常用名:4-Methylumbelliferyl Caprylate
IUPAC:4-methyl-2-oxo-2H-chromen-7-yl octanoate
IUPAC:4-methyl-2-oxo-2H-chromen-7-yl octanoate
InChI key:WZEWYQWWSCVHCP-UHFFFAOYSA-N

分子式:C18H22O4
分子量:302.37
氢键供体数 (HBD):0
氢键受体数 (HBA):2
LogP:5.28
SMILES:CCCCCCCC(=O)Oc1ccc2c(C)cc(=O)oc2c1
SMILES:CCCCCCCC(=O)Oc1ccc2c(C)cc(=O)oc2c1

4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase. MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.

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