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- HIT ID:HIT106636074
- Cas No:924-49-2
- 常用名:Gamibetal
- InChI key:YQGDEPYYFWUPGO-UHFFFAOYSA-N
- 分子式:C4H9NO3
- 分子量:119.12
- 氢键供体数 (HBD):3
- 氢键受体数 (HBA):4
- LogP:-3.969
- (R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.
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- 供应商TargetMol规格货期1-3天纯度99.96%¥ 133.001
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- 供应商ChemDiv规格货期3-5周纯度-¥ 858.001
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- 供应商Enamine规格货期4-6周纯度-¥ 264.001
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- 供应商Princeton BioMolecal Research规格货期4-6周纯度-待询1
- 供应商Apollo规格货期4-6周纯度-待询1
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