Name: 6-Azuridine
Rating: 5 (10 reviews)

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HIT ID:HIT107106605
Cas No:54-25-1
常用名:6-Azuridine
别名:氮杂尿苷, 6-Azuridine
IUPAC:2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
IUPAC:2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
InChI key:WYXSYVWAUAUWLD-SHUUEZRQSA-N

分子式:C8H11N3O6
分子量:245.191
氢键供体数 (HBD):4
氢键受体数 (HBA):7
LogP:-2.3920054
SMILES:OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ncc(=O)[nH]c1=O
SMILES:OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ncc(=O)[nH]c1=O

6-Azauridine (6-Azuridine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.6-Azuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.

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