PKM2 activator 3 | AnyMole

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HIT211540637

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HIT211540637

HIT ID:HIT211540637
Cas No:
常用名:PKM2 activator 3
IUPAC:N-(3-chloro-4-fluorophenyl)-7-fluoro-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide
IUPAC:N-(3-chloro-4-fluorophenyl)-7-fluoro-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide
InChI key:VLIHQHQPGAWJCM-UHFFFAOYSA-N

分子式:C15H11ClF2N2O3S
分子量:372.77
氢键供体数 (HBD):2
氢键受体数 (HBA):3
LogP:3.477
SMILES:Fc1ccc(NS(=O)(=O)c2cc3CCC(=O)Nc3cc2F)cc1Cl
SMILES:Fc1ccc(NS(=O)(=O)c2cc3CCC(=O)Nc3cc2F)cc1Cl

PKM2 activator 3 is a highly potent compound that activates PKM2, with an AC 50 value of 90 nM. It exhibits excellent Caco-2 permeability, a low efflux ratio, and remarkable microsomal stability. PKM2 activator 3 is particularly valuable for anticancer research purposes [1]. (AC 50: the concentration at which 50% enzyme activation occurs.)

市场产品/服务共显示2个结果

供应商
TargetMolSC
规格
货期
6-8周
纯度
-
¥ 10,600.00
1
供应商
EnamineSC
规格
货期
4-6周
纯度
-
¥ 1,084.00
1

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