Name: Amicarbazone
Rating: 5 (10 reviews)

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HIT ID:HIT211999682
Cas No:129909-90-6
常用名:Amicarbazone
别名:胺唑草酮, BAY-MKH 3586, BAY314666
IUPAC:4-amino-N-tert-butyl-5-oxo-3-(propan-2-yl)-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide
IUPAC:4-amino-N-tert-butyl-5-oxo-3-(propan-2-yl)-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide
InChI key:ORFPWVRKFLOQHK-UHFFFAOYSA-N

分子式:C10H19N5O2
分子量:241.295
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:0.95801985
SMILES:CC(C)c1nn(C(=O)NC(C)(C)C)c(=O)n1N
SMILES:CC(C)c1nn(C(=O)NC(C)(C)C)c(=O)n1N

Amicarbazone (Standard) is the standard substance of Amicarbazone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Amicarbazone (BAY-MKH3586; BAY314666) is a potent PSII inhibitor, disrupting photosynthetic electron transport by binding to the Qb domain of photosystem II. This broad-spectrum herbicide is effective through foliar and root application, showcasing rapid absorption and translocation. However, its effectiveness can be compromised by common PSII inhibitor resistance. With an IC50 value indicating high potency, amicarbazone leads to chlorosis, stunted growth, tissue necrosis, and death in sensitive plants. Despite these severe effects, it exhibits good selectivity and outperforms atrazine as a herbicide, allowing for its application at lower doses compared to traditional photosynthetic inhibitors.

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