Name: CP-465022 (maleate)
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212000050
Cas No:199656-46-7
常用名:CP-465022 (maleate)
IUPAC:(2Z)-but-2-enedioic acid; 3-(2-chlorophenyl)-2-[(1E)-2-{6-[(diethylamino)methyl]pyridin-2-yl}ethenyl]-6-fluoro-3,4-dihydroquinazolin-4-one
IUPAC:(2Z)-but-2-enedioic acid; 3-(2-chlorophenyl)-2-[(1E)-2-{6-[(diethylamino)methyl]pyridin-2-yl}ethenyl]-6-fluoro-3,4-dihydroquinazolin-4-one
InChI key:WLLUWLRVXIHECY-KSUUAYPFSA-N

分子式:C30H28ClFN4O5
分子量:579.03
氢键供体数 (HBD):0
氢键受体数 (HBA):4
LogP:5.5137267
SMILES:OC(=O)\C=C/C(O)=O.CCN(CC)Cc1cccc(\C=C\c2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1
SMILES:OC(=O)\C=C/C(O)=O.CCN(CC)Cc1cccc(\C=C\c2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1

CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity. It effectively counters the Kainate-induced response in rat cortical neurons, exhibiting an IC 50 of 25 nM. As such, CP-465022 Maleate presents a valuable instrument for studying the involvement of AMPA receptors in various physiological and pathophysiological processes [1] [2].

市场产品/服务共显示3个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~