Name: ALLO-1
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT212000055
Cas No:37468-32-9
常用名:ALLO-1
IUPAC:1-benzyl-3-(4-chlorophenyl)-5-methylimidazolidine-2,4-dione
IUPAC:1-benzyl-3-(4-chlorophenyl)-5-methylimidazolidine-2,4-dione
InChI key:GHAJNZREWTZYQJ-UHFFFAOYSA-N

分子式:C17H15ClN2O2
分子量:314.77
氢键供体数 (HBD):0
氢键受体数 (HBA):2
LogP:3.5523722
SMILES:CC1N(Cc2ccccc2)C(=O)N(C1=O)c1ccc(Cl)cc1
SMILES:CC1N(Cc2ccccc2)C(=O)N(C1=O)c1ccc(Cl)cc1

ALLO-1 is a crucial autophagy receptor responsible for facilitating the formation of autophagosomes around paternal organelles. It directly interacts with the worm LC3 homologue, LGG-1, through its LC3-interacting region (LIR) motif.

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