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HIT212003816
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HIT212003816
  • HIT ID:HIT212003816
  • Cas No:88-30-2
  • 常用名:TFM
  • IUPAC:4-nitro-3-(trifluoromethyl)phenol
    IUPAC:4-nitro-3-(trifluoromethyl)phenol
  • InChI key:ZEFMBAFMCSYJOO-UHFFFAOYSA-N
  • 分子式:C7H4F3NO3
  • 分子量:207.108
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):3
  • LogP:2.487513165333333
  • SMILES:Oc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
    SMILES:Oc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
  • TFM is a piscicide.1It is toxic to sea lamprey (P. marinus) with LC50values ranging from 1.97 to 2.11 and 2.05 to 2.21 mg/L for sac and swim-up fry, respectively, 1.6 to 2.45 mg/L for juveniles, and 1.6 to 1.63 mg/L for adults. It is also toxic to juvenile lake sturgeon (A. fulvescens) less than 100 mm in size but not to a variety of other fish species. TFM (50 μM) uncouples oxidative phosphorylation by 22 and 28% in isolated sea lamprey and rainbow trout (O. mykiss) liver, respectively.2Formulations containing TFM have been used as lampricides in the control of larval sea lamprey populations.
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