Name: Azido-PEG8-amine
Rating: 5 (10 reviews)

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HIT ID:HIT212029404
Cas No:857891-82-8
常用名:Azido-PEG8-amine
IUPAC:26-azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine
IUPAC:26-azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine
InChI key:ZSFGTBJYBWJOLZ-UHFFFAOYSA-N

分子式:C18H38N4O8
分子量:438.522
氢键供体数 (HBD):1
氢键受体数 (HBA):11
LogP:-0.8710205
SMILES:NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
SMILES:NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Azido-PEG8-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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