Name: Hydroxy-PEG9-Boc
Rating: 5 (10 reviews)

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结构编辑

类似物检索

HIT ID:HIT212036763
Cas No:2055042-66-3
常用名:Hydroxy-PEG9-Boc
IUPAC:tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate
IUPAC:tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate
InChI key:TUSKJPQJBQMEPV-UHFFFAOYSA-N

分子式:C25H50O12
分子量:542.663
氢键供体数 (HBD):1
氢键受体数 (HBA):11
LogP:-0.026506895
SMILES:CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
SMILES:CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

Hydroxy-PEG9-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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