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  3. HIT212038701
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HIT212038701
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HIT212038701
  • HIT ID:HIT212038701
  • Cas No:51524-71-1
  • 常用名:Acetyl-L-Homoserine lactone
  • IUPAC:N-[(3S)-2-oxooxolan-3-yl]acetamide
    IUPAC:N-[(3S)-2-oxooxolan-3-yl]acetamide
  • InChI key:XGSXMDQVYYCSDA-YFKPBYRVSA-N
  • 分子式:C6H9NO3
  • 分子量:143.142
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):2
  • LogP:-1.0823438
  • SMILES:CC(=O)N[C@H]1CCOC1=O
    SMILES:CC(=O)N[C@H]1CCOC1=O
  • Acetyl-L-homoserine lactone belongs to the family of N-acylated homoserine lactones (HSLs) and has an acyl chain length of two carbons. HSLs perform a role in quorum sensing; however, unlike other HSLs, acetyl-L-homoserine lactone does not elicit a response in bacteria. In an assay of carbapenem antibiotic biosynthesis, acetyl-L-homoserine lactone does not induce a response in E. carotovora. In a fluorescence assay using E. coli containing a reporter plasmid of GFP expression in response to exogenous HSLs, acetyl-L-homoserine does not elicit GFP production.
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    TargetMolSC
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    BIONET-Key OrganicsBB
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    4-6周
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