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  3. HIT212038964
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HIT212038964
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HIT212038964
  • HIT ID:HIT212038964
  • Cas No:934464-79-6
  • 常用名:Kibdelone C
  • IUPAC:(10S,12S,13R)-4-chloro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2,6,7,10,11,12,13,14-octahydro-1H-9-oxa-2-azahexaphene-1,14-dione
    IUPAC:(10S,12S,13R)-4-chloro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2,6,7,10,11,12,13,14-octahydro-1H-9-oxa-2-azahexaphene-1,14-dione
  • InChI key:NEZGGHIIKFHZCZ-MZFXBISCSA-N
  • 分子式:C29H28ClNO10
  • 分子量:585.99
  • 氢键供体数 (HBD):6
  • 氢键受体数 (HBA):10
  • LogP:2.6569185
  • SMILES:CCCc1c(Cl)c2c(O)c3CCc4c(OC)c5oc6[C@@H](O)C[C@H](O)[C@H](O)c6c(=O)c5c(O)c4-c3c(O)c2c(=O)n1C
    SMILES:CCCc1c(Cl)c2c(O)c3CCc4c(OC)c5oc6[C@@H](O)C[C@H](O)[C@H](O)c6c(=O)c5c(O)c4-c3c(O)c2c(=O)n1C
  • Kibdelone C is a member of a family of natural heterocyclic polyketides first isolated from a soil actinomycete, Kibdelosporangium. Kibdelones have been described as having potent and selective cytotoxicity against a panel of human tumor cell lines, and kibdelone C has low nanomolar effectiveness in these assays. Kibdelone C disrupts the actin cytoskeleton without directly binding actin or affecting its polymerization in vitro.
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 6,790.00
    1
  • 供应商
    BIONET-Key OrganicsBB
    规格
    货期
    4-6周
    纯度
    -
    待询
    1

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