Name: Bis-PEG4-PFP ester
Rating: 5 (10 reviews)

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类似物检索

HIT ID:HIT212048518
Cas No:1314378-12-5
常用名:Bis-PEG4-PFP ester
IUPAC:bis(2,3,4,5,6-pentafluorophenyl) 4,7,10,13-tetraoxahexadecanedioate
IUPAC:bis(2,3,4,5,6-pentafluorophenyl) 4,7,10,13-tetraoxahexadecanedioate
InChI key:RCCGHSXHOCFIBV-UHFFFAOYSA-N

分子式:C24H20F10O8
分子量:626.4
氢键供体数 (HBD):0
氢键受体数 (HBA):8
LogP:2.87
SMILES:Fc1c(F)c(F)c(OC(=O)CCOCCOCCOCCOCCC(=O)Oc2c(F)c(F)c(F)c(F)c2F)c(F)c1F
SMILES:Fc1c(F)c(F)c(OC(=O)CCOCCOCCOCCOCCC(=O)Oc2c(F)c(F)c(F)c(F)c2F)c(F)c1F

Bis-PEG4-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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