Name: Biotin-sar-oh
Rating: 5 (10 reviews)

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HIT ID:HIT212048884
Cas No:154024-76-7
常用名:Biotin-sar-oh
IUPAC:2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-methylpentanamido}acetic acid
IUPAC:2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-methylpentanamido}acetic acid
InChI key:FCDUPOLHSWBTFL-AUTRQRHGSA-N

分子式:C13H21N3O4S
分子量:315.39
氢键供体数 (HBD):3
氢键受体数 (HBA):4
LogP:-0.311
SMILES:CN(CC(O)=O)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SMILES:CN(CC(O)=O)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12

Biotin-sar-oh is a cleavable linker vital in ADC synthesis. Biotin-sar-oh joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

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