Name: Tos-PEG3-NH-Boc
Rating: 5 (10 reviews)

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HIT ID:HIT212052609
Cas No:206265-94-3
常用名:Tos-PEG3-NH-Boc
别名:PROTAC Linker 9
IUPAC:tert-butyl N-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethyl]carbamate
IUPAC:tert-butyl N-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethyl]carbamate
InChI key:IFWYDEPNEKFVRX-UHFFFAOYSA-N

分子式:C18H29NO7S
分子量:403.49
氢键供体数 (HBD):1
氢键受体数 (HBA):5
LogP:2.6466973
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCNC(=O)OC(C)(C)C
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCNC(=O)OC(C)(C)C

Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based linker utilized for the synthesis of PROTACs. It plays a critical role in facilitating the connection between a target protein and an E3 ubiquitin ligase, ultimately leading to the degradation of the target protein.

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