Name: Fmoc-NH-PEG1-C2-acid
Rating: 5 (10 reviews)

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HIT ID:HIT212068471
Cas No:1654740-73-4
常用名:Fmoc-NH-PEG1-C2-acid
IUPAC:3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]propanoic acid
IUPAC:3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]propanoic acid
InChI key:LHBCOPWWQKLECJ-UHFFFAOYSA-N

分子式:C20H21NO5
分子量:355.39
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:2.66659
SMILES:OC(=O)CCOCCNC(=O)OCC1c2ccccc2-c2ccccc12
SMILES:OC(=O)CCOCCNC(=O)OCC1c2ccccc2-c2ccccc12

Fmoc-NH-PEG1-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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